On the tire issue, any tubeless tire can take a tube by removing the valve stem and installing a tube. On the overall trip, I don't think anyone here would consider anything that far...but if so, and JMO, not sure CFM would be on the list of possible machines to take. Also with all the supplies and materials you will have to pack and take with you, not sure a 450 is the best choice either. The overland 1000 might be a better choice. Good luck though. If it does happen, document well and take lots of videos and pics for the rest of us.